Liposarcoma
Very common sarcoma
Adulthood age 40-60
Uncommon in children
Present in the extremities, retroperitoneum, and trunk
Can become very large
Frequent metases if not fully removed
(in descending order of aggressiveness)
Well-differentiated
Myxoid type
Round cell
Pleomorphic Variant
Rearrangements are common.
These tumors appear as large bulky, well-defined masses.
Lipocytes are easily seen in the well-differentiated form. In the other forms, there are cells that resemble adipocyte lineage, fat differentiation, and need to be identified. These primitive cells are lipoblasts. Lipoblasts appear as fetal fat cells, with round clear vacuoles in their c